學術論文


Academic papers

抗發炎

論文出處:J Agric Food Chem. 2005 Jan 26;53(2):469-74

論文名稱:Characterization and functional study of Antrodia camphorata lipopolysaccharide.

作  者:Cheng JJ, Yang CJ, Cheng CH, Wang YT, Huang NK, Lu MK

出 版 年:2005

分  類:抗發炎

論文結論:The functional structures and bioactivities of antrodia camphorata LPS were totally different from those of bacterial LPS. In contrary to the proinflammatory property of bacterial LPS, LPS from A. camphorata differentially reversed bacterial LPS-induced intercellular adhersion molecule-1 and monocyte adhesion; both were indicators during inflammatory process. Maybe LPS isolated from A. camphorata offers a novel therapeutic target for anti-inflammation against E. coli infection.

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論文出處:Chem Pharm Bull (Tokyo). 2006 Apr;54(4):496-500.

論文名稱:Protective effects of a neutral polysaccharide isolated from the mycelium of Antrodia cinnamomea on Propionibacterium acnes and lipopolysaccharide induced hepatic injury in mice.
 

作  者:Han HF, Nakamura N, Zuo F, Hirakawa A, Yokozawa T, Hattori M.

出 版 年:2006

分  類:抗發炎

論文結論:ACN2a, a neutral polysaccharide separated from the water extract mycelia of Antrodia cinnamomeawas, significantly prevented increases in serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) enzyme activities in mice treated with Propionibacterium acnes-LPS, indicating hepatoprotective activity in vivo.

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論文出處:World J Gastroenterol. 2006 Apr 21;12(15):2369-74.

論文名稱:Filtrate of fermented mycelia from Antrodia camphorata reduces liver fibrosis induced by carbon tetrachloride in rats.

作  者:Lin WC, Kuo SC, Lin WL, Fang HL, Wang BC

出 版 年:2006

分  類:抗發炎

論文結論:Filtrate of fermented mycelia from Antrodia camphorata (FMAC) can retard the progression of liver fibrosis induced by CCl(4) in rats.

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論文出處:Am J Chin Med. 2006;34(2):217-31.

論文名稱:Antrodia camphorata in submerged culture protects low density lipoproteins against oxidative modification.
 

作  者:Yang HL, Hseu YC, Chen JY, Yech YJ, Lu FJ, Wang HH, Lin PS, Wang BC

出 版 年:2006

分  類:抗發炎

論文結論:The antioxidant properties of Antrodia camphorata may also provide effective protection from atherosclerosis.

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論文出處:Biosci Biotechnol Biochem. 2007 Aug;71(8):1873-8. Epub 2007 Aug 7.

論文名稱:DPPH radical scavenging and semicarbazide-sensitive amine oxidase inhibitory and cytotoxic activities of Taiwanofungus camphoratus (Chang-chih).

作  者:Wang GJ, Lin SY, Wu WC, Hou WC

出 版 年:2007

分  類:抗發炎

論文結論:Extracted with cold water, methanol, and hot water from Taiwanofungus camphoratus, all have DPPH radical scavenging, semicarbazide sensitive amine oxidase inhibitory, and cytotoxic activities in B16-F10 and HT-1080 cell lines.

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論文出處:J Ethnopharmacol. 2007 Aug 15;113(1):45-53. Epub 2007 May 18.

論文名稱:Comparative anti-inflammatory characterization of wild fruiting body, liquid-state fermentation, and solid-state culture of Taiwanofungus camphoratus in microglia and the mechanism of its action.

作  者:Liu DZ, Liang HJ, Chen CH, Su CH, Lee TH, Huang CT, Hou WC, Lin SY, Zhong WB, Lin PJ, Hung LF, Liang YC.

出 版 年:2007

分  類:抗發炎

論文結論:EOC13.31 microglia was treated with various kinds of Antrodia camphorata extracts and lipopolysaccharide (LPS) and interferon-gamma (IFN-gamma) to evaluate the iNOS expression. And only methanol extracts from wild fruiting bodies were the most potent inhibitors of iNOS expression. The rank as follows: extracts of wild fruiting body>solid-state culture>liquid-state fermentation.

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論文出處:J Nat Prod. 2007 Jun;70(6):989-92. Epub 2007 Jun 9.

論文名稱:Anti-inflammatory benzenoids from Antrodia camphorata.

作  者:Chen JJ, Lin WJ, Liao CH, Shieh PC

出 版 年:2007

分  類:抗發炎

論文結論:Four new compounds (antrocamphin A (1), antrocamphin B (2), 2,3,4,5-tetramethoxybenzoyl chloride (3) and antrodioxolanone (4)) together with 13 known compounds (5~17) have been isolated from the fruiting body of Antrodia camphorata. Antrocamphin A (1), antcin A (10), and antcin B (11) exhibited potent inhibition against fMLP-induced superoxide production.

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論文出處:J Agric Food Chem. 2007 Jun 27;55(13):5007-12. Epub 2007 May 31.

論文名稱:Chemical characterization and anti-inflammatory effect of polysaccharides fractionated from submerge-cultured Antrodia camphorata mycelia.

作  者:Chen CC, Liu YW, Ker YB, Wu YY, Lai EY, Chyau CC, Hseu TH, Peng RY

出 版 年:2007

分  類:抗發炎

論文結論:

Five polysaccharide fractions (AC-1, AC-2, AC-3, AC-4, and AC-5) were obtained from Antrodia camphorata mycelia. 
In the evaluation of the DPPH* radical scavenging capability, fraction AC-1 and AC-2 polysaccharides showed the better capabilities. 
In testing with macrophage RAW264.7 cells, fraction AC-2 demonstrated a rather potent anti-inflammatory capability. 
And the lipopolysaccharide-induced NO production and the protein expression by the inducible nitric oxide synthase (iNOS) gene were inhibited by fraction AC-2 polysaccharide.

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論文出處:Acta Pharmacol Sin. 2007 Feb;28(2):258-67.

論文名稱:Modulation of inflammation-related genes of polysaccharides fractionated from mycelia of medicinal basidiomycete Antrodia camphorata.

作  者:Wu YY, Chen CC, Chyau CC, Chung SY, Liu YW

出 版 年:2007

分  類:抗發炎

論文結論:Alkaline extraction-isoelectric precipitated the polysaccharide fraction (AC-2) of Antrodia camphorata and had the ability to inhibit LPS-induced iNOS, IL-6, IL-10, MCP-5, and RANTES expression in mouse macrophages.

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論文出處:Biosci Biotechnol Biochem. 2007 Jan;71(1):23-30. Epub 2007 Jan 7.

論文名稱:Antihypertensive activities of a solid-state culture of Taiwanofungus camphoratus (Chang-chih) in spontaneously hypertensive rats.

作  者:Liu DZ, Liang YC, Lin SY, Lin YS, Wu WC, Hou WC, Su CH.

出 版 年:2007

分  類:抗發炎

論文結論:Methanol-soluble (MS) extracted of wild and solid-state cultures (SSC) of Antrodia camphorata exhibited angiotensin-converting enzyme (ACE) inhibitory activities and the antihypertensive effects. And was able to effectively lower the systolic blood pressure (SBP) and diastolic blood pressure (DBP) of spontaneously hypertensive rats.

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論文出處:J Ethnopharmacol. 2007 Mar 1;110(1):160-4. Epub 2006 Oct 4.

論文名稱:Protective effects of mycelia of Antrodia camphorata and Armillariella tabescens in submerged culture against ethanol-induced hepatic toxicity in rats.

作  者:Lu ZM, Tao WY, Zou XL, Fu HZ, Ao ZH

出 版 年:2007

分  類:抗發炎

論文結論:Administration of Antrodia camphorata markedly prevented ethanol-induced elevation of levels of serum AST, ALT, ALP, and bilirubin comparable with standard drug silymarin in rats.

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論文出處:J Nat Prod. 2008 Jul;71(7):1258-61. doi: 10.1021/np070634k. Epub 2008 Jun 4.

論文名稱:Maleimide and maleic anhydride derivatives from the mycelia of Antrodia cinnamomea and their nitric oxide inhibitory activities in macrophages.

作  者:Wu MD, Cheng MJ, Wang BC, Yech YJ, Lai JT, Kuo YH, Yuan GF, Chen IS.

出 版 年:2008

分  類:抗發炎

論文結論:Two new maleimide derivatives, antrocinnamomins A and B, and two new maleic anhydride derivatives, antrocinnamomins C and D, with three known compounds, 3-isobutyl-4-[4-(3-methyl-2-butenyloxy)phenyl]furan-2,5-dione, 3-isobutyl-4-[4-(3-methyl-2-butenyloxy)phenyl]-1H-pyrrole-2,5-dione, and 3-isobutyl-4-[4-(3-methyl-2-butenyloxy)phenyl]-1H-pyrrol-1-ol-2,5-dione, were isolated from mycelium of Antrodia cinnamomea. Antrocinnamomins A displayed significant inhibitory effect on nitric oxide (NO) production.

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論文出處:J Ethnopharmacol. 2008 Nov 20;120(2):196-203. doi: 10.1016/j.jep.2008.08.011. Epub 2008 Aug 19.

論文名稱:Immunomodulatory effect of Antrodia camphorata mycelia and culture filtrate.

作  者:Kuo MC, Chang CY, Cheng TL, Wu MJ

出 版 年:2008

分  類:抗發炎

論文結論:The mycelia fraction (Fr. M II) and culture filtrate fractions (Fr. E II and Fr. E III) were water extracts from Antrodia camphorata (AC), can modulate innate immunity and may serve as an adjuvant for tumor treatment.

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論文出處:J Agric Food Chem. 2008 Aug 27;56(16):7017-22. doi: 10.1021/jf801171x. Epub 2008 Jul 19.

論文名稱:Anti-inflammatory activities of new succinic and maleic derivatives from the fruiting body of Antrodia camphorata.

作  者:Chien SC, Chen ML, Kuo HT, Tsai YC, Lin BF, Kuo YH

出 版 年:2008

分  類:抗發炎

論文結論:New compound, trans-3-isobutyl-4-[4-(3-methyl-2-butenyloxy)phenyl]pyrrolidine-2,5-dione, increased spontaneous TNF-alpha secretion from unstimulated RAW264.7 cells but suppressed IL-6 production in LPS-stimulated cells. New compounds, cis-3-(4-hydroxyphenyl)-4-isobutyldihydrofuran-2,5-dione, 3-(4-hydroxyphenyl)-4-isobutyl-1H-pyrrole-2,5-dione, and dimethyl 2-(4-hydroxyphenyl)-3-isobutylmaleate, also suppressed IL-6 production, have an anti-inflammatory effect on macrophage-mediated responses.

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論文出處:J Ethnopharmacol. 2008 Jul 23;118(2):237-45. doi: 10.1016/j.jep.2008.04.004. Epub 2008 Apr 12.

論文名稱:Antioxidant activity of Antrodia camphorata on free radical-induced endothelial cell damage.

作  者:Hseu YC, Chen SC, Yech YJ, Wang L, Yang HL

出 版 年:2008

分  類:抗發炎

論文結論:Antrodia camphorata possesses antioxidant properties and improves endothelial function, further offering effective protection from atherosclerosis.

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