學術論文


Academic papers

抗發炎

論文出處:Int Immunopharmacol. 2008 Mar;8(3):458-67. doi: 10.1016/j.intimp.2007.11.008. Epub 2007 Dec 28.

論文名稱:Polysaccharides from Antrodia camphorata mycelia extracts possess immunomodulatory activity and inhibits infection of Schistosoma mansoni.

作  者:hen YJ, Cheng PC, Lin CN, Liao HF, Chen YY, Chen CC, Lee KM

出 版 年:2008

分  類:抗發炎

論文結論:Antrodia camphorata polysaccharides (AC-PS) appears to modulate the immune system of mice and has potential for preventing Schistosoma mansoni infection.

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論文出處:Toxicol Appl Pharmacol. 2008 Mar 1;227(2):291-8. Epub 2007 Nov 7.

論文名稱:In vivo immunomodulatory effects of Antrodia camphorata polysaccharides in a T1/T2 doubly transgenic mouse model for inhibiting infection of Schistosoma mansoni.

作  者:Cheng PC, Hsu CY, Chen CC, Lee KM.

出 版 年:2008

分  類:抗發炎

論文結論:The polysaccharides derived from Antrodia camphorata (AC-PS) appears to influence the immune system of mice into developing Th1 responses and have potential for preventing infection with Schistosoma mansoni.

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論文出處:Eur J Immunol. 2009 Sep;39(9):2482-91. doi: 10.1002/eji.200839039.

論文名稱:A triterpenoid methyl antcinate K isolated from Antrodia cinnamomea promotes dendritic cell activation and Th2 differentiation.

作  者:Yu YL, Chen IH, Shen KY, Huang RY, Wang WR, Chou CJ, Chang TT, Chu CL.

出 版 年:2009

分  類:抗發炎

論文結論:Methyl antcinate K (me-AntK), A triterpenoid isolated from Antrodia cinnamomea,  promote the ability of Dendritic cells (DC) to prime Th2 responses. And enhance immune responses and modulate DC function in immunotherapy.

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論文出處:J Ethnopharmacol. 2009 Jun 25;123(3):407-12. doi: 10.1016/j.jep.2009.03.034. Epub 2009 Mar 31.

論文名稱:Anti-angiogenic effects and mechanisms of polysaccharides from Antrodia cinnamomea with different molecular weights.

作  者:Yang CM, Zhou YJ, Wang RJ, Hu ML.

出 版 年:2009

分  類:抗發炎

論文結論:Polysaccharides from mycelia of Antrodia cinnamomea (PMAC) are anti-angiogenic in vitro and ex vivo, and the effects are likely through immunomodulation.

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論文出處:Phytother Res. 2009 Apr;23(4):582-4. doi: 10.1002/ptr.2657.

論文名稱:Inhibitory effects of antrodins A-E from Antrodia cinnamomea and their metabolites on hepatitis C virus protease.

作  者:Phuong do T, Ma CM, Hattori M, Jin JS.

出 版 年:2009

分  類:抗發炎

論文結論:Antrodin A, a succinic acid constituents isolated from Antrodia cinnamomea, have inhibitory activity on hepatitis C virus (HCV) protease. And was also detected as an in vivo metabolite of the major constituent antrodin C.

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論文出處:Int Heart J. 2009 Mar;50(2):207-20.

論文名稱:A novel inhibitory effect of Antrodia camphorata extract on vascular smooth muscle cell migration and neointima formation in mice.

作  者:Li YH, Chung HC, Liu SL, Chao TH, Chen JC

出 版 年:2009

分  類:抗發炎

論文結論:Antrodia camphorata (AC)  is an effective inhibitor of platelet-derived growth factor (PDGF)-induced rat aortic smooth muscle cell (RASMC) proliferation and migration. AC treatment reduced neointima formation in this mouse carotid ligation model.

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論文出處:Planta Med. 2009 Apr;75(5):512-6. doi: 10.1055/s-0029-1185305. Epub 2009 Feb 2.

論文名稱:New constituents with iNOS inhibitory activity from mycelium of Antrodia camphorata.

作  者:Yang SS, Wang GJ, Wang SY, Lin YY, Kuo YH, Lee TH.

出 版 年:2009

分  類:抗發炎

論文結論:

Five compounds from mycelium of Antrodia camphorata were isolated by the guidance of an inducible nitric oxide synthase (iNOS) inhibitory assay analysis. 
1. 2,4-dimethoxy-6-methylbenzene-1,3-diol and antrodin D significantly inhibited NO production without any cytotoxicity. 
2. Antroquinonol B and 4-acetyl-antroquinonol B possessed greater effects on NO inhibition, but displayed cytotoxicity at considerably higher concentrations. 
3. 2,3-(methylenedioxy)-6-methylbenzene-1,4-diol showed the lowest cell viability in treated cells.

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論文出處:J Nat Prod. 2010 Nov 29;73(11):1756-62. doi: 10.1021/np1002143. Epub 2010 Oct 28.

論文名稱:Camphoratins A-J, potent cytotoxic and anti-inflammatory triterpenoids from the fruiting body of Taiwanofungus camphoratus.

作  者:Wu SJ, Leu YL, Chen CH, Chao CH, Shen DY, Chan HH, Lee EJ, Wu TS, Wang YH, Shen YC, Qian K, Bastow KF, Lee KH.

出 版 年:2010

分  類:抗發炎

論文結論:Ten new triterpenoids, camphoratins A-J, with 12 known compounds were isolated from the fruiting body of Taiwanofungus camphoratus. Have cytotoxicity against KB and KB-VIN human cancer cell lines. And exhibited anti-inflammatory NO-production inhibition activity.

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論文出處:J Agric Food Chem. 2010 Mar 10;58(5):3153-8. doi: 10.1021/jf903638p.

論文名稱:Antrocamphin A, an anti-inflammatory principal from the fruiting body of Taiwanofungus camphoratus , and its mechanisms.

作  者:Hsieh YH, Chu FH, Wang YS, Chien SC, Chang ST, Shaw JF, Chen CY, Hsiao WW, Kuo YH, Wang SY.

出 版 年:2010

分  類:抗發炎

論文結論:The bioactive compound of Taiwanofungus camphoratus and illustrates the mechanism by which it confers its anti-inflammatory activity.

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論文出處:Nutr Cancer. 2010;62(5):593-600. doi: 10.1080/01635580903532341.

論文名稱:Dietary effect of Antrodia Camphorate extracts on immune responses in WEHI-3 leukemia BALB/c mice.

作  者:Lin SY, Sheen LY, Chiang BH, Yang JS, Pan JH, Chang YH, Hsu YM, Chiang JH, Lu CC, Wu CL, Chung JG.

出 版 年:2010

分  類:抗發炎

論文結論:Antrodia camphorata has ability to promote immune responses and to exhibited antileukemia activity in WEHI-3 leukemia BALB/c mice. And prolonged the survival rate and prevented the body weight loss.

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論文出處:Bioorg Med Chem. 2010 Sep 15;18(18):6896-904. doi: 10.1016/j.bmc.2010.07.024. Epub 2010 Jul 16.

論文名稱:Structure and functions of gamma-dodecalactone isolated from Antrodia camphorata for NK cell activation.

作  者:Chen CJ, Vijaya Krishna R, Tsai CC, Wu WH, Chao LK, Hwang KH, Chien CM, Chang HY, Chen ST.

出 版 年:2010

分  類:抗發炎

論文結論:A volatile compound, gamma-dodecalactone (gamma-DDL), was isolated from the culture medium of Antrodia camphorata. The gamma-DDL not only can induce NK cells to express CD69 but also stimulate NK cells to secrete cytotoxic molecules (FasL and granzyme B) and Th1 cytokines (TNF-alpha and INF-gamma).

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論文出處:Food Chem Toxicol. 2010 Aug-Sep;48(8-9):2319-25. doi: 10.1016/j.fct.2010.05.066. Epub 2010 Jun 1.

論文名稱:Antrodia camphorata suppresses lipopolysaccharide-induced nuclear factor-kappaB activation in transgenic mice evaluated by bioluminescence imaging.

作  者:Hseu YC, Huang HC, Hsiang CY.

出 版 年:2010

分  類:抗發炎

論文結論:The anti-inflammatory action in vivo of fermented culture broth of Antrodia camphorata in terms of LPS-induced NF-kappaB activation in transgenic mice.

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論文出處:J Agric Food Chem. 2010 Jun 23;58(12):7445-52. doi: 10.1021/jf1013764.

論文名稱:Analgesic effects and the mechanisms of anti-inflammation of ergostatrien-3beta-ol from Antrodia camphorata submerged whole broth in mice.

作  者:Huang GJ, Huang SS, Lin SS, Shao YY, Chen CC, Hou WC, Kuo YH.

出 版 年:2010

分  類:抗發炎

論文結論:An active ingredient from Antrodia camphorata (AC), Ergostatrien-3beta-ol (ST1), that anti-inflammatory mechanisms might be related to the decrease in the level of MDA, iNOS, and COX-2 in the edema paw via increasing the activities of CAT, SOD, and GPx in the liver through the suppression of TNF-alpha and NO.

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論文出處:Cancer Immunol Immunother. 2010 Aug;59(8):1259-72. doi: 10.1007/s00262-010-0852-y.

論文名稱:Promoting effect of Antrodia camphorata as an immunomodulating adjuvant on the antitumor efficacy of HER-2/neu DNA vaccine.

作  者:Huang CH, Chang CC, Lin CM, Wang ST, Wu MT, Li EI, Chang HC, Lin CC.

出 版 年:2010

分  類:抗發炎

論文結論:Antrodia camphorata represents a promising immunomodulatory adjuvant. Compared with the mice that received the HER-2/neu DNA vaccine alone, co-treatment with AC suppressed tumor growth and extended the survival rate.

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論文出處:J Agric Food Chem. 2010 Mar 24;58(6):3859-66. doi: 10.1021/jf100530c.

論文名稱:Fruiting body of Niuchangchih (Antrodia camphorata) protects livers against chronic alcohol consumption damage.

作  者:Huang CH, Chang YY, Liu CW, Kang WY, Lin YL, Chang HC, Chen YC

出 版 年:2010

分  類:抗發炎

論文結論:High dosage Antrodia camphorata showed a hypercholesterolemic effect and reduced hepatic lipids in alcohol-fed rats.

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