學術論文


Academic papers

抗發炎

論文出處:Life Sci. 2002 Jun 14;71(4):469-82.

論文名稱:Protection of oxidative damage by aqueous extract from Antrodia camphorata mycelia in normal human erythrocytes.
 

作  者:Hseu YC, Chang WC, Hseu YT, Lee CY, Yech YJ, Chen PC, Chen JY, Yang HL

出 版 年:2002

分  類:抗發炎

論文結論:Antrodia camphorata mycelia may have protective antioxidant and anticancer properties. (A. camphorata mycelia prevented the depletion of cytosolic antioxidant glutathione (GSH) and ATP in erythrocytes. Cultured human endothelial cell damage induced by AAPH was suppressed by A. camphorata mycelia. And A. camphorata mycelia exhibited significant cytotoxicity against leukemia HL-60 cells.)

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論文出處:J Agric Food Chem. 2002 May 22;50(11):3322-7.

論文名稱:Antioxidant properties of Antrodia camphorata in submerged culture.

作  者:Song TY, Yen GC

出 版 年:2002

分  類:抗發炎

論文結論:DMF showed the strongest inhibition of lipid peroxidation as a function of its concentration and marked activity in free radical scavenging. Water extract of mycelia (WEM) also showed marked activity in free radical scavenging. The rank of  antioxidant ability: DMF>DMCM>hexane extract of mycelia. (The dry matter of cultural medium (DMCM), filtrate (DMF), and different solvent extracts of mycelia from Antrodia camphorata in submerged culture (ACSC))

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論文出處:FEMS Microbiol Lett. 2002 Mar 19;209(1):63-7.

論文名稱:Antrodia camphorata polysaccharides exhibit anti-hepatitis B virus effects.

作  者:Lee IH, Huang RL, Chen CT, Chen HC, Hsu WC, Lu MK

出 版 年:2002

分  類:抗發炎

論文結論:Polysaccharides were extracted from fruiting bodies and cultured mycelia from Antrodia camphorata. Strains B86 and 35398 had substantial anti-hepatitis B e antigen activities. None of the polysaccharides exhibited cytotoxic effects.

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論文出處:J Agric Food Chem. 2003 May 21;51(11):3302-8.

論文名稱:Antioxidative and hepatoprotective effects of Antrodia camphorata extract.
 

作  者:Hsiao G, Shen MY, Lin KH, Lan MH, Wu LY, Chou DS, Lin CH, Su CH, Sheu JR.

出 版 年:2003

分  類:抗發炎

論文結論:Antrodia camphorata extract exerts effective protection against chronic chemical-induced hepatic injury in vivo, by mediating antioxidative and free radical scavenging activities.

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論文出處:J Agric Food Chem. 2003 Mar 12;51(6):1571-7.

論文名稱:Protective effects of fermented filtrate from Antrodia camphorata in submerged culture against CCl4-induced hepatic toxicity in rats.

作  者:Song TY, Yen GC

出 版 年:2003

分  類:抗發炎

論文結論:The inhibitory effect of DMF and its crude triterpenoids on lipid peroxidation occurred in a dose-response manner in an AAPH/linoleic acid system. DMF may play a role in preventing oxidative damage in living systems by up-regulating hepatic GSH-dependent enzymes to preserve the normal GSH/GSSH ratio and scavenging free radicals formed during CCl(4) metabolism.

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論文出處:Planta Med. 2004 Apr;70(4):310-4

論文名稱:Evaluation of the anti-inflammatory activity of zhankuic acids isolated from the fruiting bodies of Antrodia camphorata.

作  者:Shen YC, Wang YH, Chou YC, Chen CF, Lin LC, Chang TT, Tien JH, Chou CJ.

出 版 年:2004

分  類:抗發炎

論文結論:Fourteen compounds including zhankuic acids A, B, C, and antcin K were extracted by ethanol of the fruiting bodies of Antrodia camphorata. Inhibition of both ROS production and firm adhesion by neutrophils has no significant cytotoxic effect that could give these drugs the potential to be anti-inflammatory agents for the clinical treatment.

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論文出處:FEMS Microbiol Lett. 2004 Feb 9;231(1):137-43.

論文名稱:Anti-inflammatory activity of the extracts from mycelia of Antrodia camphorata cultured with water-soluble fractions from five different Cinnamomum species.

作  者:Shen YC, Chou CJ, Wang YH, Chen CF, Chou YC, Lu MK

出 版 年:2004

分  類:抗發炎

論文結論:Extracts from cultured mycelia of Antrodia camphorata display anti-inflammatory effects by inhibiting ROS production in human leukocytes at a pharmacologically applicable concentration. The biological activities of these extracts were further promoted when the culture medium was replaced with water-soluble fractions isolated from the wood of Cinnamomum micranthum (CM), Cinnamomum osmophloeum (CO) or Cinnamomum kotoense (CKO). And identified two lanostane-type compounds,  dehydrosulfurenic acid and 15alpha-acetyl-dehydrosulfurenic acid, which could be involved in the anti-inflammatory actions of these extracts.

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論文出處:Int Immunopharmacol. 2005 Dec;5(13-14):1914-25. Epub 2005 Jul 18.

論文名稱:Anti-inflammatory potential of Antrodia Camphorata through inhibition of iNOS, COX-2 and cytokines via the NF-kappaB pathway.

作  者:Hseu YC, Wu FY, Wu JJ, Chen JY, Chang WH, Lu FJ, Lai YC, Yang HL

出 版 年:2005

分  類:抗發炎

論文結論:Antrodia camphorata inhibits LPS induction of cytokine, iNOS and COX-2 expression by blocking NF-kappaB activation.

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論文出處:J Agric Food Chem. 2005 Jan 26;53(2):469-74

論文名稱:Characterization and functional study of Antrodia camphorata lipopolysaccharide.

作  者:Cheng JJ, Yang CJ, Cheng CH, Wang YT, Huang NK, Lu MK

出 版 年:2005

分  類:抗發炎

論文結論:The functional structures and bioactivities of antrodia camphorata LPS were totally different from those of bacterial LPS. In contrary to the proinflammatory property of bacterial LPS, LPS from A. camphorata differentially reversed bacterial LPS-induced intercellular adhersion molecule-1 and monocyte adhesion; both were indicators during inflammatory process. Maybe LPS isolated from A. camphorata offers a novel therapeutic target for anti-inflammation against E. coli infection.

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論文出處:Chem Pharm Bull (Tokyo). 2006 Apr;54(4):496-500.

論文名稱:Protective effects of a neutral polysaccharide isolated from the mycelium of Antrodia cinnamomea on Propionibacterium acnes and lipopolysaccharide induced hepatic injury in mice.
 

作  者:Han HF, Nakamura N, Zuo F, Hirakawa A, Yokozawa T, Hattori M.

出 版 年:2006

分  類:抗發炎

論文結論:ACN2a, a neutral polysaccharide separated from the water extract mycelia of Antrodia cinnamomeawas, significantly prevented increases in serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) enzyme activities in mice treated with Propionibacterium acnes-LPS, indicating hepatoprotective activity in vivo.

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論文出處:World J Gastroenterol. 2006 Apr 21;12(15):2369-74.

論文名稱:Filtrate of fermented mycelia from Antrodia camphorata reduces liver fibrosis induced by carbon tetrachloride in rats.

作  者:Lin WC, Kuo SC, Lin WL, Fang HL, Wang BC

出 版 年:2006

分  類:抗發炎

論文結論:Filtrate of fermented mycelia from Antrodia camphorata (FMAC) can retard the progression of liver fibrosis induced by CCl(4) in rats.

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論文出處:Am J Chin Med. 2006;34(2):217-31.

論文名稱:Antrodia camphorata in submerged culture protects low density lipoproteins against oxidative modification.
 

作  者:Yang HL, Hseu YC, Chen JY, Yech YJ, Lu FJ, Wang HH, Lin PS, Wang BC

出 版 年:2006

分  類:抗發炎

論文結論:The antioxidant properties of Antrodia camphorata may also provide effective protection from atherosclerosis.

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論文出處:Biosci Biotechnol Biochem. 2007 Aug;71(8):1873-8. Epub 2007 Aug 7.

論文名稱:DPPH radical scavenging and semicarbazide-sensitive amine oxidase inhibitory and cytotoxic activities of Taiwanofungus camphoratus (Chang-chih).

作  者:Wang GJ, Lin SY, Wu WC, Hou WC

出 版 年:2007

分  類:抗發炎

論文結論:Extracted with cold water, methanol, and hot water from Taiwanofungus camphoratus, all have DPPH radical scavenging, semicarbazide sensitive amine oxidase inhibitory, and cytotoxic activities in B16-F10 and HT-1080 cell lines.

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論文出處:J Ethnopharmacol. 2007 Aug 15;113(1):45-53. Epub 2007 May 18.

論文名稱:Comparative anti-inflammatory characterization of wild fruiting body, liquid-state fermentation, and solid-state culture of Taiwanofungus camphoratus in microglia and the mechanism of its action.

作  者:Liu DZ, Liang HJ, Chen CH, Su CH, Lee TH, Huang CT, Hou WC, Lin SY, Zhong WB, Lin PJ, Hung LF, Liang YC.

出 版 年:2007

分  類:抗發炎

論文結論:EOC13.31 microglia was treated with various kinds of Antrodia camphorata extracts and lipopolysaccharide (LPS) and interferon-gamma (IFN-gamma) to evaluate the iNOS expression. And only methanol extracts from wild fruiting bodies were the most potent inhibitors of iNOS expression. The rank as follows: extracts of wild fruiting body>solid-state culture>liquid-state fermentation.

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論文出處:J Nat Prod. 2007 Jun;70(6):989-92. Epub 2007 Jun 9.

論文名稱:Anti-inflammatory benzenoids from Antrodia camphorata.

作  者:Chen JJ, Lin WJ, Liao CH, Shieh PC

出 版 年:2007

分  類:抗發炎

論文結論:Four new compounds (antrocamphin A (1), antrocamphin B (2), 2,3,4,5-tetramethoxybenzoyl chloride (3) and antrodioxolanone (4)) together with 13 known compounds (5~17) have been isolated from the fruiting body of Antrodia camphorata. Antrocamphin A (1), antcin A (10), and antcin B (11) exhibited potent inhibition against fMLP-induced superoxide production.

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