學術論文


Academic papers

抗發炎

論文出處:J Nat Prod. 2010 Nov 29;73(11):1756-62. doi: 10.1021/np1002143. Epub 2010 Oct 28.

論文名稱:Camphoratins A-J, potent cytotoxic and anti-inflammatory triterpenoids from the fruiting body of Taiwanofungus camphoratus.

作  者:Wu SJ, Leu YL, Chen CH, Chao CH, Shen DY, Chan HH, Lee EJ, Wu TS, Wang YH, Shen YC, Qian K, Bastow KF, Lee KH.

出 版 年:2010

分  類:抗發炎

論文結論:Ten new triterpenoids, camphoratins A-J, with 12 known compounds were isolated from the fruiting body of Taiwanofungus camphoratus. Have cytotoxicity against KB and KB-VIN human cancer cell lines. And exhibited anti-inflammatory NO-production inhibition activity.

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論文出處:J Agric Food Chem. 2010 Mar 10;58(5):3153-8. doi: 10.1021/jf903638p.

論文名稱:Antrocamphin A, an anti-inflammatory principal from the fruiting body of Taiwanofungus camphoratus , and its mechanisms.

作  者:Hsieh YH, Chu FH, Wang YS, Chien SC, Chang ST, Shaw JF, Chen CY, Hsiao WW, Kuo YH, Wang SY.

出 版 年:2010

分  類:抗發炎

論文結論:The bioactive compound of Taiwanofungus camphoratus and illustrates the mechanism by which it confers its anti-inflammatory activity.

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論文出處:Nutr Cancer. 2010;62(5):593-600. doi: 10.1080/01635580903532341.

論文名稱:Dietary effect of Antrodia Camphorate extracts on immune responses in WEHI-3 leukemia BALB/c mice.

作  者:Lin SY, Sheen LY, Chiang BH, Yang JS, Pan JH, Chang YH, Hsu YM, Chiang JH, Lu CC, Wu CL, Chung JG.

出 版 年:2010

分  類:抗發炎

論文結論:Antrodia camphorata has ability to promote immune responses and to exhibited antileukemia activity in WEHI-3 leukemia BALB/c mice. And prolonged the survival rate and prevented the body weight loss.

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論文出處:Bioorg Med Chem. 2010 Sep 15;18(18):6896-904. doi: 10.1016/j.bmc.2010.07.024. Epub 2010 Jul 16.

論文名稱:Structure and functions of gamma-dodecalactone isolated from Antrodia camphorata for NK cell activation.

作  者:Chen CJ, Vijaya Krishna R, Tsai CC, Wu WH, Chao LK, Hwang KH, Chien CM, Chang HY, Chen ST.

出 版 年:2010

分  類:抗發炎

論文結論:A volatile compound, gamma-dodecalactone (gamma-DDL), was isolated from the culture medium of Antrodia camphorata. The gamma-DDL not only can induce NK cells to express CD69 but also stimulate NK cells to secrete cytotoxic molecules (FasL and granzyme B) and Th1 cytokines (TNF-alpha and INF-gamma).

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論文出處:Food Chem Toxicol. 2010 Aug-Sep;48(8-9):2319-25. doi: 10.1016/j.fct.2010.05.066. Epub 2010 Jun 1.

論文名稱:Antrodia camphorata suppresses lipopolysaccharide-induced nuclear factor-kappaB activation in transgenic mice evaluated by bioluminescence imaging.

作  者:Hseu YC, Huang HC, Hsiang CY.

出 版 年:2010

分  類:抗發炎

論文結論:The anti-inflammatory action in vivo of fermented culture broth of Antrodia camphorata in terms of LPS-induced NF-kappaB activation in transgenic mice.

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論文出處:J Agric Food Chem. 2010 Jun 23;58(12):7445-52. doi: 10.1021/jf1013764.

論文名稱:Analgesic effects and the mechanisms of anti-inflammation of ergostatrien-3beta-ol from Antrodia camphorata submerged whole broth in mice.

作  者:Huang GJ, Huang SS, Lin SS, Shao YY, Chen CC, Hou WC, Kuo YH.

出 版 年:2010

分  類:抗發炎

論文結論:An active ingredient from Antrodia camphorata (AC), Ergostatrien-3beta-ol (ST1), that anti-inflammatory mechanisms might be related to the decrease in the level of MDA, iNOS, and COX-2 in the edema paw via increasing the activities of CAT, SOD, and GPx in the liver through the suppression of TNF-alpha and NO.

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論文出處:Cancer Immunol Immunother. 2010 Aug;59(8):1259-72. doi: 10.1007/s00262-010-0852-y.

論文名稱:Promoting effect of Antrodia camphorata as an immunomodulating adjuvant on the antitumor efficacy of HER-2/neu DNA vaccine.

作  者:Huang CH, Chang CC, Lin CM, Wang ST, Wu MT, Li EI, Chang HC, Lin CC.

出 版 年:2010

分  類:抗發炎

論文結論:Antrodia camphorata represents a promising immunomodulatory adjuvant. Compared with the mice that received the HER-2/neu DNA vaccine alone, co-treatment with AC suppressed tumor growth and extended the survival rate.

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論文出處:J Agric Food Chem. 2010 Mar 24;58(6):3859-66. doi: 10.1021/jf100530c.

論文名稱:Fruiting body of Niuchangchih (Antrodia camphorata) protects livers against chronic alcohol consumption damage.

作  者:Huang CH, Chang YY, Liu CW, Kang WY, Lin YL, Chang HC, Chen YC

出 版 年:2010

分  類:抗發炎

論文結論:High dosage Antrodia camphorata showed a hypercholesterolemic effect and reduced hepatic lipids in alcohol-fed rats.

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論文出處: Immunology. 2010 Mar;129(3):351-62. doi: 10.1111/j.1365-2567.2009.03175.x. Epub 2009 Nov 11.

論文名稱:Administration of polysaccharides from Antrodia camphorata modulates dendritic cell function and alleviates allergen-induced T helper type 2 responses in a mouse model of asthma.

作  者:Liu KJ, Leu SJ, Su CH, Chiang BL, Chen YL, Lee YL

出 版 年:2010

分  類:抗發炎

論文結論:A. camphorata polysaccharides (GF2) may have therapeutic potential when used as an adjuvant for the immunomodulatory treatment of allergic asthma.

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論文出處:J Ethnopharmacol. 2011 Sep 1;137(1):575-84. doi: 10.1016/j.jep.2011.06.009. Epub 2011 Jun 16.

論文名稱:Anti-inflammatory effects of methanol extract of Antrodia cinnamomea mycelia both in vitro and in vivo.

作  者:Wen CL, Chang CC, Huang SS, Kuo CL, Hsu SL, Deng JS, Huang GJ.

出 版 年:2011

分  類:抗發炎

論文結論:Methanol extract of liquid cultured mycelia of Antrodia cinnamomea (MEMAC) has the anti-inflammatory property both in vitro and in vivo.

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論文出處:Nat Prod Res. 2011 Sep;25(16):1488-96. doi: 10.1080/14786410903132563. Epub 2011 Jul 8.

論文名稱:Antioxidant activities of extracts and metabolites isolated from the fungus Antrodia cinnamomea.

作  者:Wu MD, Cheng MJ, Wang WY, Huang HC, Yuan GF, Chen JJ, Chen IS, Wang BC.

出 版 年:2011

分  類:抗發炎

論文結論:N-hexane, ethyl acetate [EtOAc] and n-BuOH of the culture broth from Antrodia cinnamomea were assayed with 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging and superoxide radical scavenging (SOD) assay. In EtOAc layer exhibited the best antioxidant activity, and isolated major antioxidant metabolites.

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論文出處:Bioorg Med Chem. 2011 Jan 1;19(1):677-83. doi: 10.1016/j.bmc.2010.10.032. Epub 2010 Oct 20.

論文名稱:Biologically active constituents from the fruiting body of Taiwanofungus camphoratus.

作  者:Shi LS, Chao CH, Shen DY, Chan HH, Chen CH, Liao YR, Wu SJ, Leu YL, Shen YC, Kuo YH, Lee EJ, Qian K, Wu TS, Lee KH.

出 版 年:2011

分  類:抗發炎

論文結論:Five new benzenoids, benzocamphorins A-E, and 10 recently isolated triterpenoids, camphoratins A-J, with 23 known compounds were isolated from the fruiting body of Taiwanofungus camphoratus. These compounds may use in traditional Chinese medicine (TCM) for the treatment of inflammation and cancer-related diseases.

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論文出處:Acta Pharmacol Sin. 2011 Aug; 32(8): 981–982. Published online 2011 Aug 5. doi: 10.1038/aps.2011.104

論文名稱:Antcin A contributs to anti-inflammatory effect of Niuchangchih (Antrodia camphorata).
 

作  者:Lu ZM, Xu ZH.

出 版 年:2011

分  類:抗發炎

論文結論:

Chen et al demonstrated in human lung cancer cell A549 that antcin A was the active ingredient responsible for the anti-inflammatory effect of Antrodia camphorata, which mechanism triggered by glucocorticoids4. Hsien et al recently showed another anti-inflammatory activity compound, antrocamphin A, from Antrodia camphorata, resulted from suppressing pro-inflammatory molecule release via down-regulation of iNOS and COX-2 expression through NF-κB pathway5. Both the studies provide the potential of Antrodia camphorata to treat inflammation.

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論文出處:Acta Pharmacol Sin. 2011 Jul;32(7):904-11. doi: 10.1038/aps.2011.36. Epub 2011 May 23.

論文名稱:Antcin A, a steroid-like compound from Antrodia camphorata, exerts anti-inflammatory effect via mimicking glucocorticoids.

作  者:Chen YC, Liu YL, Li FY, Chang CI, Wang SY, Lee KY, Li SL, Chen YP, Jinn TR, Tzen JT.

出 版 年:2011

分  類:抗發炎

論文結論:Five major antcins (A, B, C, H, and K) were isolated from fruiting bodies of Antrodia camphorata. The anti-inflammatory effect of Antrodia camphorata is, at least, partly attributed to antcin A that mimics glucocorticoids and triggers translocation of glucocorticoid receptor into nucleus to initiate the suppressing inflammation.

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論文出處:Biosci Biotechnol Biochem. 2011;75(4):624-32. Epub 2011 Apr 22.

論文名稱:Macrophage mediated anti-proliferation effects of Anthodia camphorata non-polysaccharide based extracts on human hepatoma cells.

作  者:Chang CY, Cheng TJ, Chang FR, Wang HY, Kan WC, Li SL, Huang LH, Chen YC, Tsai WC, Huang CH, Cheng CH, Lee GY, Shyue SW, Chen YP, Lin KC, Chuu JJ.

出 版 年:2011

分  類:抗發炎

論文結論:Two of the extracts (extracts of Anthodia camphorata from fruiting bodies, AC-FB and from mycelium of solid-state cultures, AC-SS) had better anti-proliferation effects, implying that the macrophages might play an immunomodulatory role.

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