台灣國寶牛樟芝協會
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© Copyright 2017 by crowndesign.
All Rights Reserved.
學術論文
Academic papers
論文出處：ScientificWorldJournal. 2014;2014:745802. doi: 10.1155/2014/745802. Epub 2014 Oct 14.
論文名稱：Effect of Antrodia camphorata on inflammatory arterial thrombosis-mediated platelet activation: the pivotal role of protein kinase C.
作 者：Lu WJ, Lin SC, Lan CC, Lee TY, Hsia CH, Huang YK, Lee HC, Sheu JR
出 版 年：2014
分 類：抗發炎
論文結論：Antrodia camphorata may inhibit platelet activation by inhibiting of Ca2+ and PKC cascade and the Akt pathway. That may be a potential therapeutic agent for preventing or treating thromboembolic disorders.
論文出處：J Immunol. 2014 Mar 15;192(6):2778-86. doi: 10.4049/jimmunol.1301931. Epub 2014 Feb 14.
論文名稱：Zhankuic acid A isolated from Taiwanofungus camphoratus is a novel selective TLR4/MD-2 antagonist with anti-inflammatory properties.
作 者：Chen YF, Shiau AL, Wang SH, Yang JS, Chang SJ, Wu CL, Wu TS.
出 版 年：2014
分 類：抗發炎
論文結論：Zhankuic acid A (ZAA), a major pharmacologically active compound of Taiwanofungus camphoratus, which can compete with LPS for binding to MD-2 as a TLR4/MD-2 antagonist, may be a potential therapeutic agent for gram-negative bacterial infections.
論文出處：Biochem Pharmacol. 2014 Sep 15;91(2):217-30. doi: 10.1016/j.bcp.2014.06.026. Epub 2014 Jul 27.
論文名稱：Zhankuic acid A as a novel JAK2 inhibitor for the treatment of concanavalin A-induced hepatitis.
作 者：Chen YF, Wang SH, Chang SJ, Shiau AL, Her LS, Shieh GS, Chen CF, Chang CC, Su YC, Wu CL, Wu TS
出 版 年：2014
分 類：抗發炎
論文結論：Zhankuic acid A (ZAA), a major pharmacologically active compound, can inhibit JAK2 phosphorylation and protect against liver injury during acute hepatitis in mice.
論文出處：PLoS One. 2014 Apr 1;9(4):e93191. doi: 10.1371/journal.pone.0093191. eCollection 2014.
論文名稱：Hepatoprotective bioactivity of the glycoprotein, antrodan, isolated from Antrodia cinnamomea mycelia.
作 者：Ker YB, Peng CC, Chang WL, Chyau CC, Peng RY
出 版 年：2014
分 類：抗發炎
論文結論：Antrodan, a polysaccharide isolated from mycelia of Antrodia cinnamomea, can potentially ameliorate liver damage in vivo by suppressing oxidative stress induced by LPS.
論文出處：Int J Radiat Biol. 2014 Oct;90(10):841-52. doi: 10.3109/09553002.2014.911989. Epub 2014 Aug 11.
論文名稱：Radioprotective effects of Antrodia cinnamomea are enhanced on immune cells and inhibited on cancer cells.
作 者：Cheng PC, Huang CC, Chiang PF, Lin CN, Li LL, Lee TW, Lin B, Chen IC, Chang KW, Fan CK, Luo TY.
出 版 年：2014
分 類：抗發炎
論文結論：Antrodia cinnamomea (AC) may inhibit important immunoregulatory signaling which could be vital in the avoidance of an over-activated cytotoxic and inflammatory response of the immune system caused by radiation-induced tissue damage. AC does not provide a radioprotective effect to tumor cells but instead enhances radiation-induced inflammation and cytotoxicity in cancer.
論文出處：Food Chem Toxicol. 2014 Jul;69:150-62. doi: 10.1016/j.fct.2014.04.006. Epub 2014 Apr 18.
論文名稱：Antrodia cinnamomea profoundly exalted the reversion of activated hepatic stellate cells by the alteration of cellular proteins.
作 者：Chen YR, Chang KT, Tsai MJ, Lee CH, Huang KJ, Cheng H, Ho YP, Chen JC, Yang HH, Weng CF
出 版 年：2014
分 類：抗發炎
論文結論：Antrodia cinnamomea mycelial extract (ACME) could improve liver morphology and histological changes including collagen formation and GPT activity in the liver of thioacetamide (TAA)-injured rats.
論文出處：J Ethnopharmacol. 2014 Aug 8;155(1):154-64. doi: 10.1016/j.jep.2014.04.053. Epub 2014 May 20.
論文名稱：The medicinal fungus Antrodia cinnamomea suppresses inflammation by inhibiting the NLRP3 inflammasome.
作 者：Huang TT, Wu SP, Chong KY, Ojcius DM, Ko YF, Wu YH, Wu CY, Lu CC, Martel J, Young JD, Lai HC
出 版 年：2014
分 類：抗發炎
論文結論：Antrodia cinnamomea ethanol extract (ACEE) suppresses the secretion of IL-1β and IL-18 associated with inhibition of the NLRP3 inflammasome in macrophages, have therapeutic potential for the treatment of inflammatory diseases.
論文出處：China journal of Chinese materia medica. 2014 May;39(9):1670-4.
論文名稱：[Effect of Antrodia cinnamomea on gene expression related to aortal endothelial injury in rats with hyperlipidemia].
[Article in Chinese]
作 者：Qi J, Tao Y, Zhang J, Fu J.
出 版 年：2014
分 類：抗發炎
論文結論：Antrodia cinnamomea can alleviate endothelial lipid injury by inhibiting the expressions of LOX-1, P38MAPK and NF-kappaB in aorta and better protect aortal endothelial cells from oxidative lipid injury.
論文出處：Int J Mol Sci. 2013 Feb 26;14(3):4629-39. doi: 10.3390/ijms14034629.
論文名稱：New Anti-Inflammatory Aromatic Components from Antrodia camphorata.
作 者：Chen YC, Chiu HL, Chao CY, Lin WH, Chao LK, Huang GJ, Kuo YH.
出 版 年：2013
分 類：抗發炎
論文結論：Five benzenoids were isolated from Antrodia camphorata. That potently inhibited LPS (lipopolysaccharide)-induced nitric oxide (NO) production.
論文出處：J Agric Food Chem. 2013 May 29;61(21):5064-71. doi: 10.1021/jf303820k. Epub 2013 May 16.
論文名稱：Analgesic and anti-inflammatory bioactivities of eburicoic acid and dehydroeburicoic acid isolated from Antrodia camphorata on the inflammatory mediator expression in mice.
作 者：Deng JS, Huang SS, Lin TH, Lee MM, Kuo CC, Sung PJ, Hou WC, Huang GJ, Kuo YH.
出 版 年：2013
分 類：抗發炎
論文結論：The anti-inflammatory mechanisms of Eburicoic acid (TR1) and dehydroeburicoic acid (TR2) might be related to the decrease of inflammatory cytokines and an increase of antioxidant enzyme activity.
論文出處：J Nat Prod. 2013 Apr 26;76(4):489-94. doi: 10.1021/np300443p. Epub 2013 Mar 21.
論文名稱：Anti-inflammatory lanostanoids and lactone derivatives from Antrodia camphorata.
作 者：Liaw CC, Chen YC, Huang GJ, Tsai YC, Chien SC, Wu JH, Wang SY, Chao LK, Sung PJ, Huang HC, Kuo YH.
出 版 年：2013
分 類：抗發炎
論文結論：Four new lanostanoids and two new lactone derivatives, with four known compounds, were characterized from Antrodia camphorata. Ethyl lucidenate A, 15-O-acetylganolucidate A, 11α-hydroxy-3,7-dioxolanost-8,24(E)-dien-26- oic acid, 3,7,11-trioxo-5α-lanosta-8,24(E)-dien-26-oic acid, methyl 3,7,11,12,15,23-hexaoxo-5α-lanost-8-en-26-oate, and ethyl 3,7,11,12,15,23-hexaoxo-5α-lanost-8-en-26-oate significantly suppressed the NO concentration in LPS-treated RAW 264.7 cells.
論文出處：Free Radic Biol Med. 2013 Aug;61:285-97. doi: 10.1016/j.freeradbiomed.2013.03.024. Epub 2013 Apr 6.
論文名稱：Antroquinonol mitigates an accelerated and progressive IgA nephropathy model in mice by activating the Nrf2 pathway and inhibiting T cells and NLRP3 inflammasome.
作 者：Yang SM, Ka SM, Hua KF, Wu TH, Chuang YP, Lin YW, Yang FL, Wu SH, Yang SS, Lin SH, Chang JM, Chen A.
出 版 年：2013
分 類：抗發炎
論文結論：Antroquinonol administration substantially impeded the development of severe renal lesions (glomerular proliferation, crescents, sclerosis, and periglomerular interstitial inflammation), in mice with induced accelerated and progressive IgA nephropathy (AcP-IgAN).
論文出處：Evid Based Complement Alternat Med. 2013;2013:914524. doi: 10.1155/2013/914524. Epub 2013 May 30.
論文名稱：Ethanol Extract of Antrodia camphorata Grown on Germinated Brown Rice Suppresses Inflammatory Responses in Mice with Acute DSS-Induced Colitis.
作 者：Park DK, Park HJ.
出 版 年：2013
分 類：抗發炎
論文結論：The anti-inflammatory activity of Antrodia camphorata (AC) grown on germinated brown rice (CBR) is a promising, potential agent for preventing acute colitis through the inhibition of NF-κB signaling and its upstream signaling molecules, including MAPKs.
論文出處：Food Chem. 2013 Dec 1;141(3):3020-7. doi: 10.1016/j.foodchem.2013.03.061. Epub 2013 Apr 6.
論文名稱：Hepatoprotective effects of eburicoic acid and dehydroeburicoic acid from Antrodia camphorata in a mouse model of acute hepatic injury.
作 者：Huang GJ, Deng JS, Huang SS, Lee CY, Hou WC, Wang SY, Sung PJ, Kuo YH.
出 版 年：2013
分 類：抗發炎
論文結論：Eburicoic acid (TR1) and dehydroeburicoic acid (TR2) protect the liver from CCl4-induced hepatic damage via antioxidant and anti-inflammatory mechanisms.
論文出處：Appl Microbiol Biotechnol. 2013 Dec;97(23):9955-67. doi: 10.1007/s00253-013-5214-1. Epub 2013 Sep 24.
論文名稱：Antrodia camphorata-fermented product cultured in deep ocean water has more liver protection against thioacetamide-induced fibrosis.
作 者：Wang LC, Kuo IU, Tsai TY, Lee CL.
出 版 年：2013
分 類：抗發炎
論文結論：Antrodia camphorata-fermented product cultured in Deep ocean water (DOW-AC) prevented from thioacetamide (TAA)-induced weight loss and had more effect on inhibiting lipid peroxidation, reactive oxygen species, iNOS, and TNF-α expression. DOW-AC increased the production of Antrodia camphorata-fermented functional metabolites (triterpenoids, polysaccharides, flavonoids, and polyphenols) and had more potent effect on protection against TAA-induced liver damage and fibrosis.